'X' marks the spot in hunt for autism genes

日期:2019-03-02 09:02:09 作者:范痞 阅读:

A previously unrecognised trigger for autism may have been found, in the form of mutations that affects neuron development in a brain region important for learning and social interaction. Autism is around four times more common in boys than girls, which suggests that mutations on the X chromosome play a role, as boys lack a second X chromosome that could compensate for any genetic abnormality. Studies have identified several hundred gene candidates, but no conclusive links to a specific mutation. Now a 15-year-long international screening effort has identified two different mutations of the same X chromosome gene,