Drug defeats deadly Ebola virus infection

日期:2019-03-01 10:10:09 作者:酆扶鄄 阅读:

By Andy Coghlan An RNA-based drug has treated an infection of the deadly Ebola virus – the first drug to have been shown to do so in all recipients. Ebola Zaire virus kills 90 per cent of the people it infects. There are experimental vaccines that protect people given it before they are exposed to the virus, but there has been no drug to help those who are already infected. Now Thomas Geisbert of the Boston University School of Medicine in Massachusetts and colleagues have designed a small interfering RNA molecule that sabotages three of the virus’s vital genes. Four rhesus monkeys infected with the virus all survived after receiving the drug for seven days, starting 30 minutes after infection The treatment could be used within five years, says Geisbert, but further experiments and trials are needed to establish how long after infection it is effective. Journal reference: The Lancet, vol 375, p 1896 More on these topics: